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Holly Springs, NC – Hallway, as three football fields, connects four buildings in a new factory for the production of Fujifilm Biotechnologies in Holiology, North Carolina.
The first two buildings are prepared for the opening of this decline to produce a substance of drugs, basically a base of biological drugs, for the initial Fujifylm customers Regeneron and Johnson & Johnson. The other two buildings are still under construction, with plans for opening 2028. years.
Fujifilm’s weather could not be better, as president Donald Trump They threaten to impose tariffs on pharmaceutical people to encourage companies to become more drugs in the US, but plans for this complex are well before Trump proposed more duties.
It was taken five years and more than $ 3 billion to turn the idea into reality. And shows how hard it would be hard for drugs to quickly increase production in the United States, even a possible grace period that Trump floated.
“This is a pharmaceutical manufacturing plant, so everything must be able to be able to put into patients,” said Fujifilm biotechnology of the Director General Lars Petersen. “Everything requires extreme level of high technology, very high cleaning. Everything needs to document, everything needs to be approved later. Thus the procedure is extremely hard.”
How companies move to set up more American production, tariffs may not end up as a big problem for them as previously thought. Trump Administration on Thursday clarified This will under its trade framework with the European Union, pharmaceutical products coming from the block are subject to only 15% of tariffs, not that the administration is more applied by medicine in general.
Time Line Fujifilma to open the Holly Springs site is in line with the average industry between three and five years to start a new factory, depending on complexity, according to complexity, general director and partner in Boston Consulting Group. It helps that a new facility is identical to one Fujifilm acts in Denmark.
The company decided to start replicating its plants to speed up the process of designing and building them. The more Fujifilm, the faster I can open new sites and customers can start production there, Petersen said. Even once the first tenants are moving in this fall, we will need an American administration of food and drugs to unsubscribe before they can use the products that are made here.
Biologics are particularly complex drugs that seem because they rely on live cells to produce exactly the same thing, every time, said General Manager of Regeneron Len Len Schleifer.
“It is very expensive, very complicated and lasts very long,” Schleifer said.
When all four buildings open 2028. year, the plant should have the capacity to produce 50 million doses of medicine per year with 16 bioreactors that can each of 20,000 liters. Companies will not say exactly which drugs will be made in the facility, but it is designed to produce monoclonal antibodies.
It takes almost two months to produce one series of home drugs. The process includes growing cells that make the desired protein, purifying the resulting material, and then preparing to cross the next step in a complex pharmaceutical supply chain of pharmaceutical products. The opening of the valve at the wrong time and release only one wrong molecule from the inside can mean that the entire series is lost, Fujifilm Petersen said.
Why are the locations to increase American production
Fujifilm Diosyth biotechnology in Holly Springs, North Carolina.
Courtesy: Fujifilm Diosinth Biotehnologies
Regeneron, one of the world’s largest manufacturers in the world, signed $ 10 billion, a 10-year contract with Fujifilm for space on the new Holly Springs website, doubles its capacity to produce American products. So far, Regeneron asked to increase production, Fujifilm had a beginning of several years in the construction of the facility, so it made sense that Biotech Company has to provide space instead of saying Schleifer.
Regeneron refused to specify which medicine would produce in Holly springs. The company produces its drugs on sites of locations, including its own factories in the United States and Ireland, according to regulatory applications. Regeneron is also in the process of opening a new factory in New York, and in that state he gained another property that he could use for production.
It is one of the many biopharmaceutical companies that recently announced plans to increase American production of pharmaceutical products as Trump’s pressure on them to bring their drugs in the country.
Otherwise, they have already increased their possibilities of producing American production before Trump began to overtake tariffs especially on pharmaceutical people, who released from deletion to dozens of countries this spring. The number of American biopharmaceutical production operations in the country increased by more than 50% since 2018., according to the pharmaceutical research and American manufacturers, the main groups of lobbying industry.
The Chief Financial Officer Johnson and Johnson Joe Volk said that changes in American tax policy have made the United States a more attractive place to produce drugs. The company signed $ 2 billion, 10-year investment for the safety of space in Fujifilm’s Holly Springs site as part of a 55 billion dollar commitment to invest in the United States in the coming years. These moves will enable J & J to provide all its advanced medication from the United States, Volk said, while decapsing for the appointment to be performed in Fujifylm’s facility.
“It really comes down to good tax policy,” Volk said. “If you think about tax policy now in the United States at a 21% (corporate) tax rate, which sets us the right to the middle of the packaging,” Allowing J & J to touch in infrastructure that appears in the United States since 2017. years.
North Carolina had used from boom. Life science companies announced about $ 28 billion investment in the country since 2016. year, with a lien, he was pledged last year, according to the center of Northern Caroline Biotechnology.
Down in the street from the new Fujifilma building in Holly Springs, Amgen is building a drug production plant of $ 1 billion, following the other one he opened there in January. Genentech will break the country later this month at a 700 million dollar plant, where medication is injected into containers like bottles.
“It’s a talent,” Laura Rowley said, the vice president of the economic development of life in the biotechnology of life in northern Carolina, about what drivers in the state. “It’s here among your peers, where there is still an opportunity for companies to shine because we have that spirit to work together.”
Playing compensation
Main Photo: The view shows the contents of the Fujifilm Diosinta Biotechnology in Stockton-on-Tees, Britain 29. January 2021. years.
Lee Smith | Reuters
Biopharm companies move in the United States to make innovative products with large margins that may withstand higher costs, Almeida BCGs said. But recovering will take time.
Only 18% of the finished generic and marked Drugs come into the United States, excluding Puerto Rico, in line with analysis of 2024. Days in food and drugs by American pharmacopoeia, an organization aimed at improving the chain of supply chain. The country of origin refers to the country where the last main step production occurred, the active pharmaceutical ingredient was usually produced.
For branded injection medications – such as those who will be made in Fujifilm’s Holy Springs facility – Europe is the dominant source, and almost half of origin there.
Providing production capacities in the United States as Fujifilm, one connection company can drive away its potential exposure to tariffs in the short term, said Greg Grobs, a higher partner in McKinsey’s McKinsei’s science. Signing up with an external site can be faster and less expensive than building a new factory.
Simply moving production to the existing space can take two to three years, Almeida BCGs said. Called technical transmission, the process of production of medicine in the new location It requires planning, testing to prove that the new process acts the same, and then seek approval from the regulator.
Regardless, each company tries to understand how to prepare for tariffs, Almeida said. The graves and colleague McKinsei’s older partner Parag Parag Parag sees the same among their clients. However, they said that no one was preparing for the rate as much as 250%, the possibility of that month, the trump assigned earlier this month.
“I have not encountered any organization that is so great in their planning, because it will take it all to change the way we organized and run, and that is why we would have to say that Patel said.
In the place of Fujifilm spring holly springs, the whole point is to provide customers with flexibility, Petersen said. There are places to double the entire site, the decision that the company will do if the demand is chasing it. If Fujifilm decides to move forward, Petersen thinks it can build it in just three years, because the company becomes faster with each clone about the facility that creates.
“There’s no doubt that you have these discussions like tariffs or as a Cowlid or as any other disorder in supply chain, creates the need for flexibility,” Petersen said. “This facility was built before these discussions, but it was definitely built to handle the supply chain capabilities should require to pick up up or down.”
