New generation technologies for unlocking the superpower of the nature of the enzyme

The three dimensional form of protein is determined in the order of amino acids

The image provided by Bitbiomes

Enzymes are proteins that leads (catalyze) very specific chemical reactions. They play the necessary roles in all life forms. Some enzymes perform daily business of biology like digestion food, some are key to growth, some are for protection against toxins, and some of them give an organism unique “super-power”. For example, there is an enzyme in plants called Rubisco, which allows them to turn the sun energy into the basic construction blocks for food, namely sugar. In certain bacteria, there are enzymes that allow them to convert nitrogen gas from the atmosphere in the usable forms needed to support the whole life on earth. While people make their own enzymes, thousands of years, we found ways to use the enzymes of microorganisms, long before they were even identified. It is originally done by combining flour or grapes with folk yeast or bacteria that are placed in nature, to produce fermented products such as wine or yogurt. However, in the last century we learned how to isolate and produce enzymes themselves and use them directly in these processes. For instances, “Amylase” Enzymes, typically found in saliva and used to start breaking down the Starches We Eat, are used to modify the starch in baking flour so that it does not rapidly crystallize and make the bread “stale.”

Natural microbes (bacteria and fungi) are a rich source of useful enzymes, but only a small part of that potential diversity was made, because it was necessary to grow organism in the laboratory to study and understand it. The world is full of organisms that cannot be grown in the laboratory, at least not without very specialized techniques. This is especially true for organisms living in very unusual settings such as deep heat openings or in extremely salty water or soils. A general expression for organisms living in these harsh environments is “extremite“And they are of interest because their enzymes developed that they can” work “under unusual conditions such as high temperatures or very sour environments.

Novel Discoveri Technology

A company based in Japan is called bitbiome It has developed a new way to discover the enzymes of “Super Power” that made extremists or any other exotic category of microbes, and that this organism in the laboratory setting should never grow. Their technology begins with a microscopic sorting technique, which allows them to isolate individual bacterial cells from mixed environmental or biological role models. They can then use recently developed technologies to make many copies of this DNA bacteria and order, all without becoming more isolated bacteria. Then they use a combination of evolutionary genetics, biosion and chemical information and artificial intelligence to compare sequences and provide three dimensional characteristics of these new proteins to similar databases that include famous sequences or proteins involving familiar sequences or proteins. The sequences that are collected by Bitbiomes retain their database, which now has about 2.4 billion sequences of over a million organisms. With its sequencing technology, this database is growing for over 1 billion sequences per year. AI is instrumental in helping to identify seemingly different enzymes with similar target activities.

This is because the enzymes of different organisms will sometimes look different, either in the amino acid sequence or in a 3D structure, but will be able to implement similar reactions. This allows for herbic researchers to identify new genes to insert a standard laboratory production body of protein and create potentially interesting new versions of enzymes or proteins coded in isolated gene sequences.

This also allows you to assess the function of these newly identified enzymes or proteins. Even with AI, this discovery and “mining” process would be impossible without the possibility of sequences of individual cells. This is because the usual techniques rely on the decades of the decades named metagenomics shotguns, which often lacks bacterial population from complex samples. As a result of the deficiencies of this action technology, we still need to identify over 99% of bacterial species found on our planet.

Technology applications

There are many potential applications for this new detection of the biomomapruitring, while the production of natural development companies, they also have an internal development pipeline, also have an internal product that developed and commercial products that develop and one’s own apartment for commercial applications. Bitbiomes also offer their individual sequencing companies and academic researchers who want to analyze the microbial population at a single-cellular level. This type of research is critical, especially in areas of understanding microbiomers, but also for understanding complex microbial populations in the soil, for example, among the roots of growing crops. The bacteria have long been understood to communicate with its environment and negative and positive ways, from H. Pilos, bowel bacteria involved in stomach ulcers, to lactobacilo, known to help the hoses health.

Partnerships

Bitbiome has already found success with a partner number, including Ajinomoto, The Japanese company that provides enzymes in the food food industry for more decades. Ajinomoto food technology on food contributes to better food productivity, cost reduction and more efficient use of food. Cooperation between Bitbioma and Ajinomoto focuses on the use of bitbiometric ownership technology to discover completely new enzymes with novel’s functionalities and applications in which today so far so far so far so far so far have so far so far have been adequate solutions so far so far.

It will be fascinating to see which can be detected by new features and opportunities and how they can be used with growing bioeconomics.